Fig. 1 · Structure
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Zonisamide sodium
Carbonic Anhydrase Inhibitor
Zonisamide sodium is a potent carbonic anhydrase inhibitor, effectively targeting hCA II and hCA V with Kis of 35.2 nM and 20.6 nM, respectively. This compound exhibits neuroprotective properties by promoting anti-apoptotic mechanisms and enhancing the expression of manganese superoxide dismutase (MnSOD). Additionally, Zonisamide sodium has been shown to upregulate Hrd1, contributing to improved cardiac function in animal models of cardiac hypertrophy. Its diverse biological activities make it suitable for investigations related to seizures, Parkinson's disease, and cardiovascular research.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 68291-98-5 |
| Applications | Carbonic Anhydrase Inhibitor |
| Formula | C8H7N2NaO3S |
| Molecular Weight | 234.21 |
| Synonyms | AD 810 sodium; CI 912 sodium |
| SMILES | O=S(CC1=NOC2=C1C=CC=C2)([NH-])=O.[Na+] |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.