Fig. 1 · Structure
Documents & Downloads
Zorevunersen sodium
Scn1a Activator
Zorevunersen sodium is an antisense oligonucleotide that acts as an activator of the Scn1a gene through TANGO technology. This compound enhances Scn1a mRNA transcripts, leading to increased expression of the NaV1.1 protein. By restoring the excitability of parvalbumin interneurons, Zorevunersen sodium effectively reduces seizure frequency and improves survival in mouse models. It is a valuable tool for research focused on Dravet syndrome and related epileptic disorders.
In Stock
Free Aliquoting for Your Order
Tell us your preferred amount per vial. We’ll confirm the options.
Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Activator |
| CAS Number | 2415330-05-9 |
| Applications | Scn1a Activator |
| Formula | C234H317N71Na17O124P17S17 |
| Molecular Weight | 7197.2 (free acid) |
| Synonyms | STK-001 sodium |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.