Fig. 1 · Structure
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Zorubicin
Daunorubicin Derivative
Zorubicin is a derivative of daunorubicin that primarily targets topoisomerase II, thereby inhibiting DNA replication through the disruption of DNA polymerase activity. This compound demonstrates significant cytotoxicity against various cancer cell lines, making it a valuable reagent for research applications focused on acute leukemias and sarcomas. Its unique mechanism of action enables the exploration of therapeutic strategies in cancer biology and pharmacology.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 54083-22-6 |
| Applications | Daunorubicin Derivative |
| Formula | C34H35N3O10 |
| Molecular Weight | 645.66 |
| Synonyms | Rubidazon; Rubidazone |
| SMILES | OC1=C(C(C2=CC=CC(OC)=C2C3=O)=O)C3=C(O)C4=C1C[C@](/C(C)=N/NC(C5=CC=CC=C5)=O)(O)C[C@@H]4O[C@H]6C[C@@H]([C@@H]([C@@H](O6)C)O)N |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.