Zotarolimus

Catalog No.: A11950
mTOR inhibitor
Zotarolimus is an immunosuppressant. It is a semi-synthetic derivative of rapamycin. It was designed for use in stents with phosphorylcholine as a carrier.
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Size Price Stock Qty
1mg
$55.00
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2mg
$55.00
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5mg
$85.00
In stock
10mg
$155.00
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25mg
$315.00
In stock
50mg
$590.00
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100mg
$855.00
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10mM * 1mL in DMSO
$155.00
In stock
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Important Notice: For research use only. We do not sell to patients.

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Biological Activity
Discription Zotarolimus is an immunosuppressant. It is a semi-synthetic derivative of rapamycin. It was designed for use in stents with phosphorylcholine as a carrier.
Targets
Target Value
Product Information
Catalog Num A11950
Formula C52H79N5O12
Molecular Weight 966.21
CAS Number 221877-54-9
SMILES C[C@@H]1CC[C@H]2C[C@@H](/C(=C/C=C/C=C/[C@H](C[C@H](C(=O)[C@@H]([C@@H](/C(=C/[C@H](C(=O)C[C@H](OC(=O)[C@@H]3CCCCN3C(=O)C(=O)[C@@]1(O2)O)[C@H](C)C[C@@H]4CC[C@@H]([C@@H](C4)OC)N5C=NN=N5)C)/C)O)OC)C)C)/C)OC
Synonyms A 179578, ABT 578, Resolute, 42-(1-Tetrazolyl)rapamycin
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 1 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro DMSO 89 mg/mL (92.11 mM)
Water Insoluble
Ethanol 89 mg/mL (92.11 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 10.35 mL 51.75 mL 103.5 mL
0.5 mM 2.07 mL 10.35 mL 20.7 mL
1 mM 1.03 mL 5.17 mL 10.35 mL
5 mM 0.21 mL 1.03 mL 2.07 mL
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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