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Zotepine-d6

Stable Isotope

Zotepine-d6 is a deuterium-labeled derivative of Zotepine, a potent antipsychotic agent that acts as an antagonist of 5-HT2A, 5-HT2C, Histamine H1, α1-adrenergic, and Dopamine D2 receptors, with Kds of 2.6 nM, 3.2 nM, 3.3 nM, 7.3 nM, and 8 nM, respectively. This stable isotope is valuable for pharmacokinetic studies and metabolic research, aiding in the elucidation of the drug's mechanisms of action and its effects on neurotransmitter systems. Zotepine-d6 is useful in exploring the compound's antidepressive and anxiolytic properties in various experimental setups.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	2512222-52-3
Applications	Stable Isotope
Formula	C₁₈H₁₂D₆ClNOS
Molecular Weight	337.90
SMILES	ClC1=CC2=C(SC3=C(C=C2OCCN(C([2H])([2H])[2H])C([2H])([2H])[2H])C=CC=C3)C=C1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.