ZSTK3744 is an aryl hydrocarbon receptor (AhR) agonist that binds directly to AhR, leading to the upregulation of key target genes such as CYP1A1, CYP1B1, and TIPARP. This compound demonstrates notable cell growth inhibitory effects and induces apoptosis specifically in triple-negative breast cancer cells. Its anti-tumor properties make ZSTK3744 a valuable tool for investigating mechanisms underlying chemoresistance in triple-negative breast cancer.
ZSTK3744 is an aryl hydrocarbon receptor (AhR) agonist that binds directly to AhR, leading to the upregulation of key target genes such as CYP1A1, CYP1B1, and TIPARP. This compound demonstrates notable cell growth inhibitory effects and induces apoptosis specifically in triple-negative breast cancer cells. Its anti-tumor properties make ZSTK3744 a valuable tool for investigating mechanisms underlying chemoresistance in triple-negative breast cancer.
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