Fig. 1 · Structure
Documents & Downloads
ZXH-1-161
CRBN Modulator
ZXH-1-161 is a selective modulator of cereblon (CRBN) that induces the degradation of GSPT1 in a CRBN-dependent manner. This compound effectively inhibits the proliferation of multiple myeloma cells and demonstrates significant antitumor activity. Its unique mechanism of action makes it a valuable tool for investigating CRBN-targeted therapies in cancer research.
In Stock
Free Aliquoting for Your Order
Tell us your preferred amount per vial. We’ll confirm the options.
Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Modulator |
| CAS Number | 2407654-51-5 |
| Applications | CRBN Modulator |
| Formula | C26H24N6O3 |
| Molecular Weight | 468.51 |
| SMILES | O=C1NC(C(CC1)N2C(C3=C(C2)C(NC4=NC(NC5=CC=C6C(CCC6)=C5)=NC=C4)=CC=C3)=O)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.