AMG-47a

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Lck inhibitor

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Catalog No. A13167

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
AMG-47a 5mg A13167-5

Regular Price: $150.00

Special Price: $127.50

AMG-47a 10mg A13167-10

Regular Price: $260.00

Special Price: $221.00

AMG-47a 25mg A13167-25

Regular Price: $600.00

Special Price: $510.00

AMG-47a 50mg A13167-50

Regular Price: $1,000.00

Special Price: $850.00

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

AMG-47a is an orally bioavailable potent inhibitor of Lck and T cell proliferation. It exhibits anti-inflammatory activity (ED50 11 mg/kg) in the anti-CD3 induced production of IL-2 in mice.

AMG-47a

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Chemical Information

Catalog Num A13167
Actions Inhibitor
M. Wt 535.56
Formula C29H28F3N5O2
Solubility DMSO
Purity >98%
Storage at -20°C 2 years
CAS No. 882663-88-9
Synonyms AMG47a, Geneticin
SMILES code CC1=C(C=C(C=C1)C(=O)NC2=CC=CC(=C2)C(F)(F)F)C3=CC4=CN=C(N=C4C=C3)NCCN5CCOCC5
Chemical Name 4-Methyl-3-[2-[[2-(4-morpholinyl)ethyl]amino]-6-quinazolinyl]-N-[3-(trifluoromethyl)phenyl]benzamide

Biological Activity

Description
AMG-47a is an orally bioavailable potent inhibitor of Lck and T cell proliferation. It exhibits anti-inflammatory activity (ED50 11 mg/kg) in the anti-CD3 induced production of IL-2 in mice.

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