Target & Activity
| Target | Activity | Value |
|---|---|---|
| Maytansinoids |
Fig. 1 · Structure
Documents & Downloads
Ansamitocin P-3
Cat. No.
A13268
CAS
66584-72-3
microtubule depolymerizing agent
Ansamitocin P-3 is a maytansine analog which displays potent cytotoxicity against the human solid tumor cell lines A-549 and HT-29.
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Biological Activity
Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 66584-72-3 |
| Alternate CAS | 66547-09-9 |
| Applications | microtubule depolymerizing agent |
| Formula | C32H43ClN2O9 |
| Molecular Weight | 635.2 |
| Synonyms | Maytansinol isobutyrate |
| SMILES | C[C@@H]1[C@@H]2C[C@]([C@@H](/C=C/C=C(/CC3=CC(=C(C(=C3)OC)Cl)N(C(=O)C[C@@H]([C@]4([C@H]1O4)C)OC(=O)C(C)C)C)\C)OC)(NC(=O)O2)O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.