Apoptosis Activator 2

Apoptosis Activator

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Catalog No. A11944

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
Apoptosis Activator 2 10mg A11944-10

Regular Price: $50.00

Special Price: $40.00

Apoptosis Activator 2 25mg A11944-25

Regular Price: $110.00

Special Price: $88.00

Apoptosis Activator 2 50mg A11944-50

Regular Price: $180.00

Special Price: $144.00

Apoptosis Activator 2 100mg A11944-100

Regular Price: $285.00

Special Price: $228.00

Apoptosis Activator 2 10mM * 1mL in DMSO A11944-10mM-D

Regular Price: $55.00

Special Price: $44.00

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

Apoptosis Activator 2 strongly induces caspase-3 activation, PARP cleavage, and DNA fragmentation which leads to the destruction of cells (Apaf-1 dependent) with IC50 of ~4 μM, inactive to HMEC, PREC, or MCF-10A cells

Apoptosis Activator 2

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Chemical Information

Catalog Num A11944
Actions Activator
M. Wt 306.1
Formula C15H9Cl2NO2
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 79183-19-0
Synonyms N/A
SMILES code C1=CC=C2C(=C1)C(=O)C(=O)N2CC3=CC(=C(C=C3)Cl)Cl
Chemical Name 1-[(3,4-Dichlorophenyl)methyl]-1H-indole-2,3-dione

Biological Activity

Description
Apoptosis Activator 2 strongly induces caspase-3 activation, PARP cleavage, and DNA fragmentation which leads to the destruction of cells (Apaf-1 dependent) with IC50 of ~4 μM, inactive to HMEC, PREC, or MCF-10A cells
Targets
Caspase-3

Solubility

Solubility (25°C)* In vitro DMSO 61 mg/mL (199.25 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

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