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- Sakamoto K ,etc. Recurrent 8q24 rearrangement in blastic plasmacytoid dendritic cell neoplasm: association with immunoblastoid cytomorphology, MYC expression, and drug response. Leukemia. 2018 May 23. doi: 10.1038/s41375-018-0154-5.
- JM Sahni ,etc. Bromodomain and extraterminal protein inhibition blocks growth of triple-negative breast cancers through the suppression of Aurora kinases. Journal of Biological Chemistry, 2016, 291(45), 23756-23768.
|Storage||at -20°C 3 years Powder|
|AZD 1152-HQPA is a highly potent and selective inhibitor of Aurora B, with Ki values to be 0.36 (Aurora B) and 1369 nM (Aurora A) respectively and has a high specificity versus a panel of 50 other kinases.|
|Solubility (25°C) *||In vitro||DMSO||102 mg/mL (200.96 mM)|
|Water||<1 mg/mL (<1 mM)|
|Ethanol||3 mg/mL (5.91 mM)|
|In vivo||30% PEG400/0.5% Tween80/5% propylene glycol||30 mg/mL|
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
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