AZD8330

Catalog No.: A10115
MEK Inhibitor
AZD8330 is a novel, selective, non-ATP competitive MEK 1/2 inhibitor with IC50 of 7 nM. Phase 1.
Grouped product items
Product Name Price Stock Qty
AZD8330 5mg
$110.00
In stock
AZD8330 10mg
$200.00
In stock
AZD8330 50mg
$620.00
In stock
AZD8330 100mg
$1,080.00
In stock
AZD8330 10mM * 1mL in DMSO
$160.00
In stock
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Important Notice: For research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Adooq's AZD8330 has been cited by 1 publications
  • Saeko Yoshioka, .et al. , Int J Tryptophan Res, 2022, Nov 30;15 PMID: 36467776
  • Biological Activity
    Discription AZD8330 is a novel, selective, non-ATP competitive MEK 1/2 inhibitor with IC50 of 7 nM. Phase 1.
    Targets
    Target Value
    Product Information
    Catalog Num A10115
    Formula C16H17FIN3O4
    Molecular Weight 461.2
    CAS Number 869357-68-6
    SMILES CC1=CC(=C(N(C1=O)C)NC2=C(C=C(C=C2)I)F)C(=O)NOCCO
    Storage

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    Solubility
    In vitro (25°C) DMSO 88 mg/mL (190.79 mM)
    Water Insoluble
    Ethanol 88 mg/mL (190.79 mM)
    In vivo 0.5% hydroxyethyl cellulose+0.1% Tween 80 28 mg/mL
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 21.68 mL 108.41 mL 216.83 mL
    0.5 mM 4.34 mL 21.68 mL 43.37 mL
    1 mM 2.17 mL 10.84 mL 21.68 mL
    5 mM 0.43 mL 2.17 mL 4.34 mL
    Useful Calculator

    This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

    Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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    Please check COA/MSDS for correct molecular weight.

    Calculate the dilution required to prepare a stock solution.
    This equation is commonly abbreviated as: C1V1 = C2V2

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