Bafetinib (INNO-406)

Bafetinib ((INNO-406) is a dual Bcr-Abl/Lyn tyrosine kinase inhibitor for the potential treatment of leukemia.
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Product Name Price Stock Qty
Bafetinib 5mg
$75.00
In stock
Bafetinib 10mg
$130.00
In stock
Bafetinib 50mg
$390.00
In stock
Bafetinib 100mg
$480.00
In stock
Bafetinib (INNO-406) 10mM * 1mL in DMSO
$174.00
In stock
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Adooq Products cited in reputable paper
Adooq's Bafetinib (INNO-406) has been cited by 5 publications
  • Yusuke Kimata, .et al. , Life Sci Alliance, 2023, Feb 27;6(5):e202201657 PMID: 36849250
  • Li T, .et al. , Oncogene, 2018, Nov;37(47):6180-6194 PMID: 30013190
  • S. Dallari, .et al. , Nat Commun, 2017, 8: 14830 PMID: 28368000
  • Andrea Haerzschel, .et al. , Ann Hematol, 2016, 95(12): 1979-1988 PMID: 27542958
  • Magdalena Winiarska, .et al. , MAbs., 2014, 6(5): 1300-1313 PMID: 25517315
  • Biological Activity
    Discription Bafetinib ((INNO-406) is a dual Bcr-Abl/Lyn tyrosine kinase inhibitor for the potential treatment of leukemia.
    Targets
    Target Value
    Product Information
    Catalog Num A10119
    Formula C30H31F3N8O
    Molecular Weight 576.6
    CAS Number 859212-16-1
    SMILES CC1=C(C=C(C=C1)NC(=O)C2=CC(=C(C=C2)CN3CC[C@@H](C3)N(C)C)C(F)(F)F)NC4=NC=CC(=N4)C5=CN=CN=C5
    Synonyms NS-187
    Storage

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    Solubility
    In vitro (25°C) DMSO 92 mg/mL (159.55 mM)
    Water Insoluble
    Ethanol Insoluble
    In vivo 0.5% methylcellulose+0.2% Tween 80 28 mg/mL
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 17.34 mL 86.72 mL 173.43 mL
    0.5 mM 3.47 mL 17.34 mL 34.69 mL
    1 mM 1.73 mL 8.67 mL 17.34 mL
    5 mM 0.35 mL 1.73 mL 3.47 mL
    Useful Calculator

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    Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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    Please check COA/MSDS for correct molecular weight.

    Calculate the dilution required to prepare a stock solution.
    This equation is commonly abbreviated as: C1V1 = C2V2

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