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Publications citing Adooq Products
Chemical Information
| Catalog Num | A15762 |
|---|---|
| Actions | Inhibitor |
| M. Wt | 464.56 |
| Formula | C29H28N4O2 |
| Solubility | DMSO |
| Purity | >98% |
| Storage | at -20°C 2 years |
| CAS No. | 1207293-36-4 |
| Synonyms | BI 847325, BI847325 |
| SMILES code | CCNC(C#CC1=CC=C2C(NC(/C2=C(NC3=CC=C(CN(C)C)C=C3)/C4=CC=CC=C4)=O)=C1)=O |
| Chemical Name | (Z)-3-(3-((4-((dimethylamino)methyl)phenylamino)(phenyl)methylene)-2-oxoindolin-6-yl)-N-ethylpropiolamide |
Description |
BI-847325 is an orally bioavailable, and selective dual MEK/Aurora kinase inhibitor with IC50 of 3 nM, 25 nM, 15 nM, 25 nM, and 4 nM for Xenopus laevis Aurora B, human Aurora A and Aurora C, as well as human MEK1 and MEK2, respectively. Phase 1. | ||||||||||
Targets |
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