BMS 599626 HCl (AC480)

Catalog No.: A11209
EGFR Inhibitor
BMS 599626 is an orally bioavailable inhibitor of the HER1, HER2 and HER4 tyrosine kinases (IC50=22, 32 and 190 nM, respectively) with potential antineoplastic activity.
Grouped product items
Product Name Price Stock Qty
BMS 599626 HCl 5mg
$80.00
In stock
BMS 599626 HCl 10mg
$140.00
In stock
BMS 599626 HCl 50mg
$400.00
In stock
BMS 599626 HCl 100mg
$700.00
In stock
BMS 599626 HCl (AC480) 10mM * 1mL in DMSO
$150.00
In stock
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Important Notice: For research use only. We do not sell to patients.

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Biological Activity
Discription BMS 599626 is an orally bioavailable inhibitor of the HER1, HER2 and HER4 tyrosine kinases (IC50=22, 32 and 190 nM, respectively) with potential antineoplastic activity.
Product Information
Catalog Num A11209
Formula C27H27FN8O3.HCl
Molecular Weight 567.1
CAS Number 873837-23-1
SMILES CC1=C2C(=NC=NN2C=C1NC(=O)OC[C@@H]3COCCN3)NC4=CC5=C(C=C4)N(N=C5)CC6=CC(=CC=C6)F.Cl
Synonyms BMS-599626, BMS599626, AC-480
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro (25°C) DMSO 104 mg/mL (196.02 mM)
Water Insoluble
Ethanol 18 mg/mL (33.92 mM)
In vivo 30% PEG400+0.5% Tween80+5% propylene glycol 28 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 17.63 mL 88.17 mL 176.34 mL
0.5 mM 3.53 mL 17.63 mL 35.27 mL
1 mM 1.76 mL 8.82 mL 17.63 mL
5 mM 0.35 mL 1.76 mL 3.53 mL
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