BMS-708163 (Avagacestat)

Catalog No.: A10157
Gamma-secretase inhibitor
BMS-708163 is an oral gamma secretase inhibitor designed for selective inhibition of amyloid beta synthesis.
Grouped product items
Product Name Price Stock Qty
BMS-708163 5mg
$110.00
In stock
BMS-708163 10mg
$200.00
In stock
BMS-708163 50mg
$680.00
In stock
BMS-708163 100mg
$1,180.00
In stock
BMS-708163 10mM * 1mL in DMSO
$174.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500

Important Notice: For research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Biological Activity
Discription BMS-708163 is an oral gamma secretase inhibitor designed for selective inhibition of amyloid beta synthesis.
Targets
Target Value
Product Information
Catalog Num A10157
Formula C20H17ClF4N4O4S
Molecular Weight 520.8
CAS Number 1146699-66-2
SMILES C1=CC(=CC=C1S(=O)(=O)N(CC2=C(C=C(C=C2)C3=NOC=N3)F)[C@H](CCC(F)(F)F)C(=O)N)Cl
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro DMSO 90 mg/mL (172.78 mM)
Water Insoluble
Ethanol Insoluble
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 19.2 mL 96.01 mL 192.01 mL
0.5 mM 3.84 mL 19.2 mL 38.4 mL
1 mM 1.92 mL 9.6 mL 19.2 mL
5 mM 0.38 mL 1.92 mL 3.84 mL
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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