CCT128930

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AKT Inhibitor

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Catalog No. A11031

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
CCT128930 10mg A11031-10

Regular Price: $128.00

Special Price: $102.40

CCT128930 25mg A11031-25

Regular Price: $256.00

Special Price: $204.80

CCT128930 50mg A11031-50

Regular Price: $450.00

Special Price: $360.00

CCT128930 100mg A11031-100

Regular Price: $720.00

Special Price: $576.00

CCT128930 10mM * 1mL in DMSO A11031-10mM-D

Regular Price: $103.00

Special Price: $82.40

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

CCT128930 is an ATP-competitive AKT inhibitor that is a potent, advanced lead pyrrolopyrimidine compound exhibiting selectivity for AKT over PKA, achieved by targeting a single amino acid difference.

CCT128930

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Chemical Information

Catalog Num A11031
Actions Inhibitor
M. Wt 341.8
Formula C18H20ClN5
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 885499-61-6
Synonyms CCT-128930
SMILES code C1CN(CCC1(CC2=CC=C(C=C2)Cl)N)C3=NC=NC4=C3C=CN4
Chemical Name 4-[(4-Chlorophenyl)methyl]-1-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-4-piperidinamine

Biological Activity

Description
CCT128930 is an ATP-competitive AKT inhibitor that is a potent, advanced lead pyrrolopyrimidine compound exhibiting selectivity for AKT over PKA, achieved by targeting a single amino acid difference.
Targets
Akt2 (Cell-free assay) p70 S6K (Cell-free assay) PKA (Cell-free assay)
6 nM120 nM168 nM

Solubility

Solubility (25°C) * In vitro DMSO 68 mg/mL (198.92 mM)
Water <1 mg/mL (<1 mM)
Ethanol 6 mg/mL (17.55 mM)
In vivo 1% DMSO/30% polyethylene glycol/1% Tween 80 11 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

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