Cerpegin

Catalog No.: A77374
20S Proteasome Inhibitor
Cerpegin is a potent inhibitor of the 20S proteasome, which plays a critical role in the degradation of ubiquitinated proteins. This compound exhibits significant biological activities including anti-inflammatory, analgesic, and antiulcer effects, making it a valuable tool in research focused on proteasome-related pathways and therapeutic applications. Its mechanism of action allows for exploration in models of neuroprotection and various inflammatory conditions.
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5mg
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Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionCerpegin is a potent inhibitor of the 20S proteasome, which plays a critical role in the degradation of ubiquitinated proteins. This compound exhibits significant biological activities including anti-inflammatory, analgesic, and antiulcer effects, making it a valuable tool in research focused on proteasome-related pathways and therapeutic applications. Its mechanism of action allows for exploration in models of neuroprotection and various inflammatory conditions.
Product Information
Catalog NumA77374
FormulaC10H11NO3
Molecular Weight193.20
CAS Number129748-28-3
SMILESO=C1OC(C)(C)C(C=CN2C)=C1C2=O
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