CK-636

Arp2/3 inhibitor

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Catalog No. A13827

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
CK-636 10mg A13827-10
$65.00
CK-636 25mg A13827-25
$160.00
CK-636 50mg A13827-50
$300.00
CK-636 100mg A13827-100
$480.00
CK-636 10mM * 1mL in DMSO A13827-10mM-D
$80.00

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

CK-636 is a Arp2/3 complex inhibitor. CK-636 binds between Arp2 and Arp3, where it appears to block movement of Arp2 and Arp3 into their active conformation.

CK-636

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Chemical Information

Catalog Num A13827
Actions Inhibitor
M. Wt 284.09833
Formula C16H16N2OS
Solubility DMSO
Purity >98%
Storage at -20°C 2 years
CAS No. 442632-72-6
Synonyms CK636, CK 636
SMILES code CC1=C(C2=CC=CC=C2N1)CCNC(=O)C3=CC=CS3
Chemical Name N-[2-(2-Methyl-1H-indol-3-yl)ethyl]-2-thiophenecarboxamide

Biological Activity

Description
CK-636 is a Arp2/3 complex inhibitor. CK-636 binds between Arp2 and Arp3, where it appears to block movement of Arp2 and Arp3 into their active conformation.
Targets
Human Arp2/3 complex Fission yeast Arp2/3 complex Bovine Arp2/3 complex
4 μM24 μM32 μM

Solubility

Solubility (25°C)* In vitro DMSO 57 mg/mL (200.43 mM)
Water <1 mg/mL (<1 mM)
Ethanol 50 mg/mL (175.82 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

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