Target & Activity
| Target | Activity | Value |
|---|---|---|
| BTK | <1 nM |
Fig. 1 · Structure
Documents & Downloads
CNX-774
Cat. No.
A13233
CAS
1202759-32-7
BTK Inhibitor
CNX-774 is a potent Btk inhibitor (IC50 < 1 nM)
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Biological Activity
Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 1202759-32-7 |
| Applications | BTK Inhibitor |
| Formula | C26H22FN7O3 |
| Molecular Weight | 499.5 |
| SMILES | CNC(=O)C1=NC=CC(=C1)OC2=CC=C(C=C2)NC3=NC=C(C(=N3)NC4=CC(=CC=C4)NC(=O)C=C)F |
Storage & Solubility
In Vitro Solubility
Reported Solubility
| Solvent | Reported Solubility |
|---|---|
| DMSO | 89 mg/mL (178.18 mM) |
| Water | Insoluble |
| Ethanol | 2 mg/mL (4 mM) |
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.