Cyclopamine Hedgehog signaling inhibitor

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Catalog No. A10249

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Product Name Catalog No. Price Qty
Cyclopamine 5mg A10249-5
Cyclopamine 10mg A10249-10
Cyclopamine 25mg A10249-25
Cyclopamine 50mg A10249-50

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

Cyclopamine is a Smo or hedgehog signaling pathway inhibitor.


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Chemical Information

Catalog Num A10249
Actions Inhibitor
M. Wt 411.6
Formula C27H41NO2
Solubility DMSO
Purity >98%
Storage at -20°C 2 years
CAS No. 4449-51-8
Synonyms 11-deoxojervine
SMILES code C[[email protected]]1C[C@@H]2[[email protected]]([[email protected]]([C@]3(O2)CC[[email protected]]4[C@@H]5CC=C6C[[email protected]](CC[C@@]6([[email protected]]5CC4=C3C)C)O)C)NC1
Chemical Name (3β,23R)-17,23-Epoxyveratraman-3-ol

Biological Activity

Cyclopamine is a Smo or hedgehog signaling pathway inhibitor.
Smoothened (TM3Hh12 cells)
46 nM


Solubility (25°C)* In vitro DMSO <1 mg/mL (<1 mM)
Water <1 mg/mL (<1 mM)
Ethanol 4 mg/mL heating (9.71 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

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