Ezetimibe (Zetia)

Ezetimibe is a compound that lowers cholesterol. It acts by decreasing cholesterol absorption in the intestine. Ezetimibe localises at the brush border of the small intestine, where ezetimibe inhibits the absorption of cholesterol from the intestine.
Grouped product items
Product Name Price Stock Qty
Ezetimibe 25mg
$40.00
In stock
Ezetimibe 100mg
$100.00
In stock
Ezetimibe (Zetia) 10mM * 1mL in DMSO
$66.00
In stock
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Adooq Products cited in reputable paper
Adooq's Ezetimibe (Zetia) has been cited by 1 publications
  • Nihei W, .et al. , J Lipid Res, 2018, Nov; 59(11): 2181-2187 PMID: 30242108
  • Biological Activity
    Discription Ezetimibe is a compound that lowers cholesterol. It acts by decreasing cholesterol absorption in the intestine. Ezetimibe localises at the brush border of the small intestine, where ezetimibe inhibits the absorption of cholesterol from the intestine.
    Product Information
    Catalog Num A10379
    Formula C24H21F2NO3
    Molecular Weight 409.4
    CAS Number 163222-33-1
    SMILES C1=CC(=CC=C1[C@@H]2[C@H](C(=O)N2C3=CC=C(C=C3)F)CC[C@@H](C4=CC=C(C=C4)F)O)O
    Synonyms Zetia , Ezetrol
    Storage

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    Solubility
    In vitro (25°C) DMSO 75 mg/mL (183.19 mM)
    Water Insoluble
    Ethanol 75 mg/mL (183.19 mM)
    In vivo 2% DMSO+30% PEG 300+5% Tween 80+ddH2O 9 mg/mL
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 24.43 mL 122.13 mL 244.26 mL
    0.5 mM 4.89 mL 24.43 mL 48.85 mL
    1 mM 2.44 mL 12.21 mL 24.43 mL
    5 mM 0.49 mL 2.44 mL 4.89 mL
    Useful Calculator

    This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

    Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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    Please check COA/MSDS for correct molecular weight.

    Calculate the dilution required to prepare a stock solution.
    This equation is commonly abbreviated as: C1V1 = C2V2

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