We use analytics and advertising cookies, which you can accept or reject; see our privacy policy.

Current choice:

Fig. 1 · Structure
Cat. No.
A12163
CAS No.
65646-68-6
Formula
C26H33NO2
Mol. Weight
391.55

Documents & Downloads

Fenretinide

Cat. No. A12163 CAS 65646-68-6

RAR agonist

Fenretinide is a synthetic retinoid agonist. It is an antiproliferative, antioxidant and anticancer agent with a long half-life in vivo.

In Stock

Notify me when the price drops

For laboratory research use only. We do not sell to patients.

Free Aliquoting for Your Order

Tell us your preferred amount per vial. We’ll confirm the options.

Biological Activity

Cellular Effect

Cell Line Activity Value Description Reference
Astrocyte EC50 2.399 μM Antiproliferative activity against mouse astrocyte cells by MTT assay [PMID: 17417631]
BHK-21 CC50 31.5 μM Cytotoxicity against BHK21 cells in presence of ATP by Celltiter-Glo assay [PMID: 28689975]
CWR22R GI50 3.23 μM Growth inhibition of human CWR22Rv1 cells by MTT assay [PMID: 25634130]
Daoy GI50 5 μM Antiproliferative activity against human Daoy cells assessed as inhibition of cell growth incubated for 24 to 96 hrs by MTT assay [PMID: 33636537]
G-401 IC50 5 μM Cytotoxicity against human G401 cells assessed as cell survival after 3 days by MTS assay [PMID: 18556204]
HEK-293T IC50 18.7 μM Inhibition of mouse Ido2 transfected in HEK293T cells using L-tryptophan as substrate assessed as kynurenine formation after 45 mins by spectrophotometric analysis [PMID: 23122865]
HEK-293T IC50 59.9 μM Inhibition of mouse Ido1 transfected in HEK293T cells using L-tryptophan as substrate assessed as kynurenine formation after 45 mins by spectrophotometric analysis [PMID: 23122865]
HuCCT-1 IC50 6 μM Cytotoxicity against human HuCCT1 cells after 72 hrs by MTT assay [PMID: 22440084]
LNCaP GI50 2.69 μM Growth inhibition of human LNCAP cells by MTT assay [PMID: 25634130]
LNCaP IC50 7.5 μM Growth inhibition of human LNCaP cells after 6 days by MTT assay [PMID: 15615521]
MCF7 IC50 0.15 μM Growth inhibition of human MCF7 cells after 6 days by MTT assay [PMID: 15615521]
MCF7 GI50 4.65 μM Growth inhibition of human MCF7 cells by MTT assay [PMID: 25634130]
MDA-MB-231 GI50 11.05 μM Growth inhibition of human MDA-MB-231 cells by MTT assay [PMID: 25634130]
MDA-MB-231 IC50 7.7 μM Growth inhibition of human MDA-MB-231 cells after 6 days by MTT assay [PMID: 15615521]
MDA-MB-468 GI50 6.02 μM Growth inhibition of human MDA-MB-468 cells by MTT assay [PMID: 25634130]
Medulloblastoma cell EC50 0.204 μM Antiproliferative activity against mouse medulloblastoma cells harboring heterozygous ptch1 gene by MTT assay [PMID: 17417631]
MIA PaCa-2 IC50 7 μM Cytotoxicity against human MIAPaCa2 cells after 72 hrs by MTT assay [PMID: 22440084]
ONS-76 GI50 2 μM Antiproliferative activity against human ONS-76 cells assessed as inhibition of cell growth incubated for 24 to 96 hrs by MTT assay [PMID: 33636537]
PC-3 GI50 2 μM Cytotoxicity against human PC3 cells after 72 hrs by MTT assay [PMID: 26780304]
PC-3 GI50 3.54 μM Growth inhibition of human PC3 cells by MTT assay [PMID: 25634130]

20 records · Scroll to view more

Specifications

Manufacturer Adooq Bioscience
Actions Agonist
CAS Number 65646-68-6
Applications RAR agonist
Formula C26H33NO2
Molecular Weight 391.55
Synonyms 4-HPR; (4-Hydroxyphenyl)retinamide
SMILES
CC1=C(C(CCC1)(C)C)/C=C/C(=C/C=C/C(=C/C(=O)NC2=CC=C(C=C2)O)/C)/C

Storage & Solubility

In Vitro Solubility

Reported Solubility

SolventReported Solubility
DMSO 69 mg/mL (176.22 mM)
Water Insoluble
Ethanol 69 mg/mL (176.22 mM)

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Added to your cart

View Cart Checkout
Loading...