H-1152 dihydrochloride

ROCK inhibitor

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Catalog No. A15102

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
H-1152 dihydrochloride 5mg A15102-5
$135.00
H-1152 dihydrochloride 10mg A15102-10
$252.00
H-1152 dihydrochloride 50mg A15102-50
$550.00

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

H-1152 dihydrochloride, an isoquinolinesulfonamide derivative, is a more specific, stronger and membrane-permeable inhibitor of Rho-kinase with a Ki value of 1.6 nM, but poor inhibitor of other serine/threonine kinases.

H-1152 dihydrochloride

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Chemical Information

Catalog Num A15102
Actions Inhibitor
M. Wt 392.34
Formula C16H23Cl2N3O2S
Solubility DMSO
Purity >98%
Storage at -20°C 2 years
CAS No. 871543-07-6
Synonyms H 1152 dihydrochloride, H1152 dihydrochloride
SMILES code CC1CNCCCN1S(=O)(=O)C2=CC=CC3=CN=CC(=C32)C.Cl.Cl
Chemical Name 4-methyl-5-[(2-methyl-1,4-diazepan-1-yl)sulfonyl]isoquinoline;dihydrochloride

Biological Activity

Description
H-1152 dihydrochloride, an isoquinolinesulfonamide derivative, is a more specific, stronger and membrane-permeable inhibitor of Rho-kinase with a Ki value of 1.6 nM, but poor inhibitor of other serine/threonine kinases.

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