IKK-16 IKK Inhibitor

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Catalog No. A12836

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
IKK-16 10mg A12836-10
$80.00
IKK-16 25mg A12836-25
$150.00
IKK-16 50mg A12836-50
$220.00
IKK-16 100mg A12836-100
$350.00
IKK-16 10mM * 1mL in DMSO A12836-10mM-D
$98.00

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

IKK 16 is a selective IκB kinase (IKK) inhibitor for IKK-2, IKK complex and IKK-1 with IC50 of 40 nM, 70 nM and 200 nM, respectively.

IKK-16

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Chemical Information

Catalog Num A12836
Actions Inhibitor
M. Wt 483.63
Formula C28H29N5OS
Solubility DMSO
Purity >98%
Storage at -20°C 2 years
CAS No. 873225-46-8
Synonyms IKK 16, IKK16
SMILES code C1CCN(C1)C2CCN(CC2)C(=O)C3=CC=C(C=C3)NC4=NC=CC(=N4)C5=CC6=CC=CC=C6S5
Chemical Name Piperidine,1-[4-[(4-benzo[b]thien-2-yl-2-pyrimidinyl)amino]benzoyl]-4-(1-pyrrolidinyl)

Biological Activity

Description
IKK 16 is a selective IκB kinase (IKK) inhibitor for IKK-2, IKK complex and IKK-1 with IC50 of 40 nM, 70 nM and 200 nM, respectively.
Targets
IKK2 (Cell-free assay) IKK complex (Cell-free assay) IKK1 (Cell-free assay)
40 nM70 nM200 nM

Solubility

Solubility (25°C) * In vitro DMSO 97 mg/mL (200.56 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
In vivo 30% PEG400/0.5% Tween80/5% propylene glycol 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

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