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PORCN inhibitor

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Catalog No. A13978

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
IWP-L6 10mg A13978-10

Regular Price: $85.00

Special Price: $68.00

IWP-L6 25mg A13978-25

Regular Price: $180.00

Special Price: $144.00

IWP-L6 50mg A13978-50

Regular Price: $300.00

Special Price: $240.00

IWP-L6 10mM * 1mL in DMSO A13978-10mM-D

Regular Price: $99.00

Special Price: $79.20

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

IWP-L6 is a potent inhibitor of Porcupine (Porcn), a membrane-bound O-acyltransferase (MBOAT) (EC50 = 0.5 nM).


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Chemical Information

Catalog Num A13978
Actions Inhibitor
M. Wt 472.58
Formula C25H20N4O2S2
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1427782-89-5
Synonyms IWP L6, IWPL6
Chemical Name N-(5-Phenyl-2-pyridinyl)-2-[(3,4,6,7-tetrahydro-4-oxo-3-phenylthieno[3,2-d]pyrimidin-2-yl)thio]acetamide

Biological Activity

IWP-L6 is a potent inhibitor of Porcupine (Porcn), a membrane-bound O-acyltransferase (MBOAT) (EC50 = 0.5 nM).
0.5 nM(EC50)


Solubility (25°C)* In vitro DMSO 25 mg/mL heating (52.9 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

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