KRX-0402

DNA repair inhibitor

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Catalog No. A15459

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
KRX-0402 5mg A15459-5

Regular Price: $150.00

Special Price: $120.00

KRX-0402 10mg A15459-10

Regular Price: $280.00

Special Price: $224.00

KRX-0402 25mg A15459-25

Regular Price: $550.00

Special Price: $440.00

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

KRX-0402 is a small molecule that was specifically designed to block the DNA repair protein, MGMT. MGMT confers resistance to certain alkylating agents, such as temozolomide and BCNU, that are commonly used to treat brain cancer, melanoma and non-Hodgkin??s lymphoma.

KRX-0402

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Chemical Information

Catalog Num A15459
Actions Inhibitor
M. Wt 241.25
Formula C12H11N5O
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1000874-21-4
Synonyms O6-benzyl guanine, O6-BG
SMILES code C1=CC=C(C=C1)COC2=NC(=NC3=C2NC=N3)N
Chemical Name 6-phenylmethoxy-7H-purin-2-amine

Biological Activity

Description
KRX-0402 is a small molecule that was specifically designed to block the DNA repair protein, MGMT. MGMT confers resistance to certain alkylating agents, such as temozolomide and BCNU, that are commonly used to treat brain cancer, melanoma and non-Hodgkin??s lymphoma.

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