Methazolastone

Catalog No.: A10575

DNA damage inducer

Methazolastone

Methazolastone Chemical Structure

CAS NO. 85622-93-1

Methazolastone is a DNA damage inducer.

Availability: In stock

Package Price Qty
10 mg
$30.00
50 mg
$100.00
100 mg
$120.00
10mM * 1mL in DMSO
$65.00
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Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.
  • VJ Herbener, .et al. Considering the Experimental Use of Temozolomide in Glioblastoma Research, Biomedicines, 2020, Jun 4;8(6):E151 PMID: 32512726

Biological Activity

Methazolastone is a DNA damage inducer.
Targets
DNA replication (L-1210, L-1210/BCNU cells)
In vitro (25°C) DMSO 39 mg/mL (200.87 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
In vivo 1% DMSO/30% polyethylene glycol/1% Tween 80 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 51.76 mL 258.8 mL 517.6 mL
0.5 mM 10.35 mL 51.76 mL 103.52 mL
1 mM 5.18 mL 25.88 mL 51.76 mL
5 mM 1.04 mL 5.18 mL 10.35 mL

*The above data is based on the productmolecular weight 193.2. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A10575
Actions Inducer
M. Wt 193.2
Formula C7H7N5O2
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 85622-93-1
Synonyms Temozolomide, Temodar, Temodal
SMILES CN1C(=O)N2C=NC(=C2N=N1)C(=O)N

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