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DNA damage inducer

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Catalog No. A10575

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
Methazolastone 10mg A10575-10
Methazolastone 50mg A10575-50
Methazolastone 100mg A10575-100
Methazolastone 10mM * 1mL in DMSO A10575-10mM-D

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

Methazolastone is a DNA damage inducer.


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Chemical Information

Catalog Num A10575
Actions Inducer
M. Wt 193.2
Formula C7H7N5O2
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 85622-93-1
Synonyms Temozolomide, Temodar, Temodal
SMILES code CN1C(=O)N2C=NC(=C2N=N1)C(=O)N
Chemical Name 4-Methyl-5-oxo-2,3,4,6,8-pentazabicyclo[4.3.0]nona-2,7,9-triene-9-carboxamide

Biological Activity

Methazolastone is a DNA damage inducer.
DNA replication (L-1210, L-1210/BCNU cells)


Solubility (25°C) * In vitro DMSO 39 mg/mL (200.87 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
In vivo 1% DMSO/30% polyethylene glycol/1% Tween 80 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 51.76 mL 258.8 mL 517.6mL
0.5 mM 10.35 mL 51.76 mL 103.52 mL
1 mM 5.18 mL 25.88 mL 51.76 mL
5 mM 1.04 mL 5.18 mL 10.35 mL

*The above data is based on the productmolecular weight 193.2. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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