Letrozole

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Aromatase inhibitor

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Catalog No. A10523

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
Letrozole 10mg A10523-10

Regular Price: $20.00

Special Price: $16.00

Letrozole 50mg A10523-50

Regular Price: $50.00

Special Price: $40.00

Letrozole 100mg A10523-100

Regular Price: $80.00

Special Price: $64.00

Letrozole 10mM * 1mL in DMSO A10523-10mM-D

Regular Price: $65.00

Special Price: $52.00

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

Letrozole is an Aromatase inhibitor. CGS 20267 is a new non-steroidal compound which potently inhibits aromatase in vitro (IC50 of 11.5 nM) and in vivo (ED50 of 1–3 μg/kg p.o.)

Letrozole

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Chemical Information

Catalog Num A10523
Actions Inhibitor
M. Wt 285.3
Formula C17H11N5
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 112809-51-5
Synonyms CGS 20267, Femara, Piroxicam
SMILES code C1=CC(=CC=C1C#N)C(C2=CC=C(C=C2)C#N)N3C=NC=N3
Chemical Name 4,4'-(1H-1,2,4-Triazol-1-ylmethylene)bisbenzonitrile

Biological Activity

Description
Letrozole is an Aromatase inhibitor. CGS 20267 is a new non-steroidal compound which potently inhibits aromatase in vitro (IC50 of 11.5 nM) and in vivo (ED50 of 1–3 μg/kg p.o.)
Targets
Aromatase (Cell-free assay)
0.07 nM-20 nM

Solubility

Solubility (25°C) * In vitro DMSO 57 mg/mL (199.78 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
In vivo 0.5% CMC 10 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

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