Letrozole

Catalog No.: A10523
Aromatase inhibitor
Letrozole is an Aromatase inhibitor. CGS 20267 is a new non-steroidal compound which potently inhibits aromatase in vitro (IC50 of 11.5 nM) and in vivo (ED50 of 1?€?3 μg/kg p.o.)
Grouped product items
Product Name Price Stock Qty
Letrozole 10mg
$20.00
In stock
Letrozole 50mg
$50.00
In stock
Letrozole 100mg
$65.00
In stock
Letrozole 10mM * 1mL in DMSO
$65.00
In stock
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Adooq Products cited in reputable paper
Adooq's Letrozole has been cited by 1 publications
  • WEI LIU, .et al. , Exp Ther Med, 2015, Oct; 10(4): 1297-1302 PMID: 26622481
  • Biological Activity
    Discription Letrozole is an Aromatase inhibitor. CGS 20267 is a new non-steroidal compound which potently inhibits aromatase in vitro (IC50 of 11.5 nM) and in vivo (ED50 of 1?€?3 μg/kg p.o.)
    Targets
    Target Value
    Product Information
    Catalog Num A10523
    Formula C17H11N5
    Molecular Weight 285.3
    CAS Number 112809-51-5
    SMILES C1=CC(=CC=C1C#N)C(C2=CC=C(C=C2)C#N)N3C=NC=N3
    Synonyms CGS 20267, Femara, Piroxicam
    Storage

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    Solubility
    In vitro (25°C) DMSO 50 mg/mL (175.25 mM)
    Water Insoluble
    Ethanol Insoluble
    In vivo 0.5% CMC Na 9 mg/mL
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 35.05 mL 175.25 mL 350.51 mL
    0.5 mM 7.01 mL 35.05 mL 70.1 mL
    1 mM 3.51 mL 17.53 mL 35.05 mL
    5 mM 0.7 mL 3.51 mL 7.01 mL
    Useful Calculator

    This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

    Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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    Please check COA/MSDS for correct molecular weight.

    Calculate the dilution required to prepare a stock solution.
    This equation is commonly abbreviated as: C1V1 = C2V2

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