LY364947

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TGFβR-I Inhibitor

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Catalog No. A13446

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
LY364947 10mg A13446-10

Regular Price: $60.00

Special Price: $54.00

LY364947 25mg A13446-25

Regular Price: $120.00

Special Price: $108.00

LY364947 50mg A13446-50

Regular Price: $200.00

Special Price: $180.00

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

LY364947 is a diheteroaryl-substituted pyrazole compound used as a selective, ATP-competitive inhibitor of TGF-βRI (TGF-β Receptor I kinase).

LY364947

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Chemical Information

Catalog Num A13446
Actions Inhibitor
M. Wt 272.3
Formula C17H12N4
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 396129-53-6
Synonyms HTS 466284 ,TGF-β RI Kinase Inhibitor
SMILES code C1=CC=C2C(=C1)C(=CC=N2)C3=C(NN=C3)C4=CC=CC=N4
Chemical Name 4-[3-(2-pyridinyl)-1H-pyrazol-4-yl]-quinoline

Biological Activity

Description
LY364947 is a diheteroaryl-substituted pyrazole compound used as a selective, ATP-competitive inhibitor of TGF-βRI (TGF-β Receptor I kinase).
Targets
TGFβRI (Cell-free assay) RIPK2 (Cell-free assay) CK1δ (Cell-free assay) TGFβRII (Cell-free assay) MLK-7K (Cell-free assay)
59 nM0.11 μM0.22 μM0.4 μM1.4 μM

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