Target & Activity
| Target | Activity | Value |
|---|---|---|
| ALK2 | 32 nM | |
| ALK1 | 46 nM | |
| ALK6 | 9.83 μM | |
| ALK3 | 10.8 μM |
Fig. 1 · Structure
Documents & Downloads
ML347
Cat. No.
A14298
CAS
1062368-49-3
BMP receptor inhibitor
ML347 is a selective BMP receptor inhibitor .
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Biological Activity
Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 1062368-49-3 |
| Applications | BMP receptor inhibitor |
| Formula | C22 H16N4O |
| Molecular Weight | 352.39 |
| Synonyms | ML 347,ML-347 |
| SMILES | COC1=CC=C(C=C1)C2=CN3C(=C(C=N3)C4=C5C=CC=NC5=CC=C4)N=C2 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
| Solvent | Reported Solubility |
|---|---|
| DMSO | 9 mg/mL (25.53 mM) |
| Water | Insoluble |
| Ethanol | Insoluble |
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.