NNC 55-0396

Calcium channel blocker

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Catalog No. A15188

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
NNC 55-0396 10mg A15188-10

Regular Price: $175.00

Special Price: $140.00

NNC 55-0396 50mg A15188-50

Regular Price: $495.00

Special Price: $396.00

NNC 55-0396 100mg A15188-100

Regular Price: $885.00

Special Price: $708.00

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

NNC 55-0396, Mibefradil derivative, is a highly selective T-type calcium channel blocker; displays IC50 values of 6.8 and > 100 μM for inhibition of Cav3.1 T-type channels and HVA currents respectively in INS-1 cells.

NNC 55-0396

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Chemical Information

Catalog Num A15188
Actions Blocker
M. Wt 564.56
Formula C30H40Cl2FN3O2
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 357400-13-6
Synonyms NNC 55-0396 dihydrochloride
SMILES code CC(C)C1C2=C(CCC1(CCN(C)CCCC3=NC4=CC=CC=C4N3)OC(=O)C5CC5)C=C(C=C2)F.Cl.Cl
Chemical Name (1S,2S)-2-[2-[[3-(1H-Benzimidazol-2-yl)propyl]methylamino]ethyl]-6-fluoro-1,2,3,4-tetrahydro-1-(1-methylethyl)-2-naphthalenyl cyclopropanecarboxylate dihydrochloride

Biological Activity

Description
NNC 55-0396, Mibefradil derivative, is a highly selective T-type calcium channel blocker; displays IC50 values of 6.8 and > 100 μM for inhibition of Cav3.1 T-type channels and HVA currents respectively in INS-1 cells.

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