NVP-TNKS656

TNKS2 inhibitor

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Catalog No. A15786

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
NVP-TNKS656 5mg A15786-5
$230.00
NVP-TNKS656 10mg A15786-10
$400.00
NVP-TNKS656 25mg A15786-25
$690.00

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

NVP-TNKS656 is a highly potent, selective, and orally active TNKS2 inhibitor with IC50 of 6 nM; > 300 fold selectivity against PARP1 and PARP2.

NVP-TNKS656

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Chemical Information

Catalog Num A15786
Actions Inhibitor
M. Wt 494.58
Formula C27H34N4O5
Solubility DMSO
Purity >98%
Storage at -20°C 2 years
CAS No. 1419949-20-4
Synonyms TNKS656, TNKS-656
SMILES code COC1=CC=C(C=C1)C(=O)C2CCN(CC2)CC(=O)N(CC3CC3)CC4=NC(=O)C5=C(N4)CCOC5
Chemical Name N-(cyclopropylmethyl)-2-[4-(4-methoxybenzoyl)piperidin-1-yl]-N-[(4-oxo-1,5,7,8-tetrahydropyrano[4,3-d]pyrimidin-2-yl)methyl]acetamide

Biological Activity

Description
NVP-TNKS656 is a highly potent, selective, and orally active TNKS2 inhibitor with IC50 of 6 nM; > 300 fold selectivity against PARP1 and PARP2.
Targets

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