Fig. 1 · Structure

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PD 166793

Cat. No. A15307 CAS 199850-67-4

Broad spectrum MMP inhibitor

PD166793 is a cell-permeable compound that strongly inhibits MMP (matrix metalloproteinase) -2 , -3, and -13, and weakly inhibits AMP deaminase, MMP-1, -7, -9, and -14.

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Biological Activity

Target & Activity

Target Activity Value
MMP-2 IC50 4 nM
MMP-3 IC50 7 nM
MMP-13 IC50 8 nM
MMP-1 IC50 6.0 μM
MMP-7 IC50 7.2 μM
MMP-9 IC50 7.9 μM

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 199850-67-4
Applications Broad spectrum MMP inhibitor
Formula C17H18BrNO4S
Molecular Weight 412.3
SMILES
CC(C)C(C(=O)O)NS(=O)(=O)C1=CC=C(C=C1)C2=CC=C(C=C2)Br

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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