RepSox (SJN 2511)

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Catalog No. A11762

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
RepSox (SJN 2511) 10mg A11762-10

Regular Price: $90.00

Special Price: $76.50

RepSox (SJN 2511) 25mg A11762-25

Regular Price: $200.00

Special Price: $170.00

RepSox (SJN 2511) 50mg A11762-50

Regular Price: $350.00

Special Price: $297.50

RepSox (SJN 2511) 100mg A11762-100

Regular Price: $600.00

Special Price: $510.00

RepSox (SJN 2511) 10mM * 1mL in DMSO A11762-10mM-D

Regular Price: $65.00

Special Price: $55.25

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

RepSox (SJN 2511) is a selective inhibitor of the TGF-β type I receptor ALK5 (IC50 values are 0.004 and 0.023 μM for ALK5 autophosphorylation and ALK5 binding respectively).

RepSox (SJN 2511)

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Chemical Information

Catalog Num A11762
Actions N/A
M. Wt 287.32
Formula C17H13N5
Solubility DMSO
Purity >98%
Storage at -20°C 2 years
CAS No. 446859-33-2
Synonyms E-616452, SJN 2511, ALK 5 inhibitor
SMILES code CC1=CC=CC(=N1)C2=C(C=NN2)C3=NC4=C(C=C3)N=CC=C4
Chemical Name 2-(3-(6-Methylpyridine-2-yl)-1H-pyr?azol-4-yl)-1,5-naphthyridine

Biological Activity

Description
RepSox (SJN 2511) is a selective inhibitor of the TGF-β type I receptor ALK5 (IC50 values are 0.004 and 0.023 μM for ALK5 autophosphorylation and ALK5 binding respectively).
Targets
TGFβR1(ALK5) (Cell-free assay)
4 nM

Solubility

Solubility (25°C)* In vitro DMSO 57 mg/mL (198.38 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

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