RO4929097
RO4929097 is an orally bioavailable, small-molecule gamma secretase (GS) inhibitor with an IC50 of 4 nM.
Free Delivery on orders over $500
Research use only. We do not sell to patients.
Loading distributor info...
Adooq Products cited in reputable paper
Adooq's RO4929097 has been cited by 1 publications
- Hirosumi Tamura, .et al. , Oncol Rep, 2018, Aug; 40(2): 635-646 PMID: 29917168
Biological Activity
| Description | RO4929097 is an orally bioavailable, small-molecule gamma secretase (GS) inhibitor with an IC50 of 4 nM. | |||||
|---|---|---|---|---|---|---|
| Targets |
| |||||
| Cell Research |
|
Product Information
| Catalog Num | A10802 |
|---|---|
| Formula | C22H20F5N3O3 |
| Molecular Weight | 469.4 |
| CAS Number | 847925-91-1 |
| SMILES | CC(C)(C(=O)NCC(C(F)(F)F)(F)F)C(=O)N[C@H]1C2=CC=CC=C2C3=CC=CC=C3NC1=O |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
Solubility
| In vitro (25°C) | DMSO | 92 mg/mL (195.99 mM) | |
| Water | Insoluble | ||
| Ethanol | 16 mg/mL | ||
| In vivo | 2% DMSO+30% PEG 300+5% Tween+ddH2O | 9 mg/mL | |
| * <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. | |||
Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 21.3 mL | 106.52 mL | 213.04 mL |
| 0.5 mM | 4.26 mL | 21.3 mL | 42.61 mL |
| 1 mM | 2.13 mL | 10.65 mL | 21.3 mL |
| 5 mM | 0.43 mL | 2.13 mL | 4.26 mL |
Useful Calculator
This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:
Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)
Please check COA/MSDS for correct molecular weight.
Calculate the dilution required to prepare a stock solution.This equation is commonly abbreviated as: C1V1 = C2V2
