RO4929097

Catalog No.: A10802
Gamma-secretase inhibitor
RO4929097 is an orally bioavailable, small-molecule gamma secretase (GS) inhibitor with an IC50 of 4 nM.
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Product Name Price Stock Qty
RO4929097 5mg
$100.00
In stock
RO4929097 10mg
$180.00
In stock
RO4929097 50mg
$560.00
In stock
RO4929097 200mg
$1,380.00
In stock
RO4929097 10mM * 1mL in DMSO
$153.00
In stock
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Important Notice: For research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Adooq's RO4929097 has been cited by 1 publications
  • Hirosumi Tamura, .et al. , Oncol Rep, 2018, Aug; 40(2): 635-646 PMID: 29917168
  • Biological Activity
    Discription RO4929097 is an orally bioavailable, small-molecule gamma secretase (GS) inhibitor with an IC50 of 4 nM.
    Targets
    Target Value
    Product Information
    Catalog Num A10802
    Formula C22H20F5N3O3
    Molecular Weight 469.4
    CAS Number 847925-91-1
    SMILES CC(C)(C(=O)NCC(C(F)(F)F)(F)F)C(=O)N[C@H]1C2=CC=CC=C2C3=CC=CC=C3NC1=O
    Storage

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    Solubility
    In vitro (25°C) DMSO 92 mg/mL (195.99 mM)
    Water Insoluble
    Ethanol 16 mg/mL
    In vivo 2% DMSO+30% PEG 300+5% Tween+ddH2O 9 mg/mL
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 21.3 mL 106.52 mL 213.04 mL
    0.5 mM 4.26 mL 21.3 mL 42.61 mL
    1 mM 2.13 mL 10.65 mL 21.3 mL
    5 mM 0.43 mL 2.13 mL 4.26 mL
    Useful Calculator

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    Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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    Please check COA/MSDS for correct molecular weight.

    Calculate the dilution required to prepare a stock solution.
    This equation is commonly abbreviated as: C1V1 = C2V2

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