Fig. 1 · Structure

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Saikosaponin B2

Cat. No. A14600 CAS 58316-41-9

Prostanoid activator

Saikosaponin B2 is a saponin activator.

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Biological Activity

Cellular Effect

Cell Line Activity Value Description Reference
A549 IC50 > 80 μM Cytotoxicity against human A549 cells after 48 hrs by MTT assay [PMID: 26883148]
Bcap37 IC50 > 80 μM Cytotoxicity against human Bcap37 cells after 48 hrs by MTT assay [PMID: 26883148]
Hep 3B2 IC50 > 80 μM Cytotoxicity against human Hep3B cells after 48 hrs by MTT assay [PMID: 26883148]
HepG2 IC50 35.1 μM Cytotoxicity against human HepG2 cells after 48 hrs by MTT assay [PMID: 26883148]
MCF7 IC50 > 80 μM Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay [PMID: 26883148]
MRC5 CC50 383 μM Cytotoxicity against human MRC5 cells incubated for 96 hrs by XTT assay [PMID: 32845145]

Specifications

Manufacturer Adooq Bioscience
Actions Activator
CAS Number 58316-41-9
Applications Prostanoid activator
Formula C42H68O13
Molecular Weight 780.99
SMILES
CC1C(C(C(C(O1)OC2CCC3(C(C2(C)CO)CCC4(C3C=CC5=C6CC(CCC6(C(CC54C)O)CO)(C)C)C)C)O)OC7C(C(C(C(O7)CO)O)O)O)O

Storage & Solubility

In Vitro Solubility

Reported Solubility

SolventReported Solubility
DMSO 91 mg/mL (116.52 mM)

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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