Saxagliptin (BMS-477118)

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DPP-4 Inhibitor

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Catalog No. A11109

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
Saxagliptin 10mg A11109-10

Regular Price: $90.00

Special Price: $76.50

Saxagliptin 25mg A11109-25

Regular Price: $150.00

Special Price: $127.50

Saxagliptin 50mg A11109-50

Regular Price: $240.00

Special Price: $204.00

Saxagliptin 100mg A11109-100

Regular Price: $350.00

Special Price: $297.50

Saxagliptin (BMS-477118) 10mM * 1mL in DMSO A11109-10mM-D

Regular Price: $91.00

Special Price: $77.35

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

Saxagliptin (BMS-477118) is a new dipeptidyl peptidase-4 (DPP-4) inhibitor with IC50 of 50 nM.

Saxagliptin (BMS-477118)

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Chemical Information

Catalog Num A11109
Actions Inhibitor
M. Wt 315.4
Formula C18H25N3O2
Solubility DMSO
Purity >98%
Storage at -20°C 2 years
CAS No. 361442-04-8
Synonyms BMS-477118,Onglyza
SMILES code C1[[email protected]@H]2C[[email protected]@H]2N([[email protected]@H]1C#N)C(=O)[[email protected]](C34CC5CC(C3)CC(C5)(C4)O)N
Chemical Name (1S,3S,5S)-2-[(2S)-2-amino-2-(3-hydroxy-1-adamantyl)acetyl]-2-azabicyclo[3.1.0]hexane-3-carbonitrile

Biological Activity

Description
Saxagliptin (BMS-477118) is a new dipeptidyl peptidase-4 (DPP-4) inhibitor with IC50 of 50 nM.
Targets
DPP-4
26 nM

Solubility

Solubility (25°C) * In vitro DMSO 63 mg/mL (199.74 mM)
Water 63 mg/mL (199.74 mM)
Ethanol 24 mg/mL (76.09 mM)
In vivo Saline 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

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