SB-705498 TRPV1 antagonist

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Catalog No. A11143

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
SB-705498 5mg A11143-5
$80.00
SB-705498 10mg A11143-10
$150.00
SB-705498 50mg A11143-50
$650.00
SB-705498 100mg A11143-100
$1,050.00
SB-705498 10mM * 1mL in DMSO A11143-10mM-D
$127.00

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

SB-705498 is a potent, selective and orally bioavailable TRPV1 antagonist.

SB-705498

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Chemical Information

Catalog Num A11143
Actions Antagonist
M. Wt 428.0
Formula C17H16BrF3N4O
Solubility DMSO
Purity >98%
Storage at -20°C 2 years
CAS No. 501951-42-4
Synonyms SB705498
SMILES code C1CN(C[C@@H]1NC(=O)NC2=CC=CC=C2Br)C3=NC=C(C=C3)C(F)(F)F
Chemical Name 1-(2-Bromophenyl)-3-{(3R)-1-[5-(trifluoromethyl)-2-pyridinyl]-3-pyrrolidinyl}urea

Biological Activity

Description
SB-705498 is a potent, selective and orally bioavailable TRPV1 antagonist.
Targets
hTRPV1 hTRPV1
7.6(pKi)7.1(pIC50)

Solubility

Solubility (25°C)* In vitro DMSO 86 mg/mL (200.35 mM)
Water <1 mg/mL (<1 mM)
Ethanol 20 mg/mL (46.59 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

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