SB225002

Catalog No.: A14209
CXCR2 antagonist
SB225002 is a potent, and selective CXCR2 antagonist with IC50 of 22 nM for inhibiting interleukin IL-8 binding to CXCR2, > 150-fold selectivity over the other 7-TMRs tested.
Grouped product items
Product Name Price Stock Qty
SB225002 10mg
$70.00
In stock
SB225002 25mg
$140.00
In stock
SB225002 50mg
$220.00
In stock
SB225002 10mM * 1mL in DMSO
$65.00
In stock
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Biological Activity
Discription SB225002 is a potent, and selective CXCR2 antagonist with IC50 of 22 nM for inhibiting interleukin IL-8 binding to CXCR2, > 150-fold selectivity over the other 7-TMRs tested.
Targets
Target Value
Product Information
Catalog Num A14209
Formula C13H10BrN3O4
Molecular Weight 352.14
CAS Number 182498-32-4
SMILES C1=CC=C(C(=C1)NC(=O)NC2=C(C=C(C=C2)[N+](=O)[O-])O)Br
Synonyms SB-225002, SB 225002
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro (25°C) DMSO 64 mg/mL (181.74 mM)
Water Insoluble
Ethanol Warmed: 3 mg/mL (8.51 mM)
In vivo 2% DMSO+30% PEG 300+5% Tween 80+ddH2O 4 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 28.4 mL 141.99 mL 283.98 mL
0.5 mM 5.68 mL 28.4 mL 56.8 mL
1 mM 2.84 mL 14.2 mL 28.4 mL
5 mM 0.57 mL 2.84 mL 5.68 mL
Useful Calculator

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