AMD-070 HCl

Catalog No.: A14997

CXCR4 antagonist

AMD-070 HCl Chemical Structure

CAS NO. 880549-30-4

AMD-070 hydrochloride is a potent and selective antagonist of CXCR4 with an IC50 value of 13 nM in a CXCR4 125I-SDF inhibition binding assay, inhibit the replication of T-tropic HIV-1 (NL4.3 strain) in MT-4 cells and PBMCs.

Availability: In stock

Package Price Qty
5 mg
$140.00
10 mg
$250.00
50 mg
$700.00
Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

AMD-070 hydrochloride is a potent and selective antagonist of CXCR4 with an IC50 value of 13 nM in a CXCR4 125I-SDF inhibition binding assay, inhibit the replication of T-tropic HIV-1 (NL4.3 strain) in MT-4 cells and PBMCs.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 21.79 mL 108.97 mL 217.93 mL
0.5 mM 4.36 mL 21.79 mL 43.59 mL
1 mM 2.18 mL 10.9 mL 21.79 mL
5 mM 0.44 mL 2.18 mL 4.36 mL

*The above data is based on the productmolecular weight 458.86. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A14997
Actions Antagonist
M. Wt 458.86
Formula C21H30Cl3N5
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 880549-30-4
Synonyms AMD070 hydrochloride, AMD 070 hydrochloride
SMILES C1CC(C2=C(C1)C=CC=N2)N(CCCCN)CC3=NC4=CC=CC=C4N3.Cl

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