Simeprevir

Catalog No.: A11580
HCV NS3/4A protease inhibitor
Simeprevir is a potent inhibitor of HCV NS3/4A protease (Ki = 0.36 nM) and viral replication (replicon EC50 = 7.8 nM).
Grouped product items
Product Name Price Stock Qty
Simeprevir 5mg
$45.00
In stock
Simeprevir 10mg
$77.00
In stock
Simeprevir 50mg
$225.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500

Important Notice: For research use only. We do not sell to patients.

Not your Region? View all Distributors

Adooq Products cited in reputable paper
Biological Activity
Discription Simeprevir is a potent inhibitor of HCV NS3/4A protease (Ki = 0.36 nM) and viral replication (replicon EC50 = 7.8 nM).
Product Information
Catalog Num A11580
Formula C38H47N5O7S2
Molecular Weight 749.96
CAS Number 923604-59-5
SMILES COC1=CC=C(C(O[C@H]2CC(C(N(C)CCCC/C=C\[C@H]3C[C@@]3(C(NS(=O)(C4CC4)=O)=O)NC5=O)=O)[C@H]5C2)=CC(C6=NC(C(C)C)=CS6)=N7)C7=C1C
Synonyms TMC435, TMC435350, TMC-435350
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro DMSO 90 mg/mL (120.01 mM)
Water Insoluble
Ethanol 4 mg/mL (5.33 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 13.33 mL 66.67 mL 133.34 mL
0.5 mM 2.67 mL 13.33 mL 26.67 mL
1 mM 1.33 mL 6.67 mL 13.33 mL
5 mM 0.27 mL 1.33 mL 2.67 mL
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

  • Mass

    Concentration

    Volume

    Molecular Weight

Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

  • C1

    V1

    C2

    V2

  • Calculator Reset
Keywords: buy Simeprevir | Simeprevir Supplier | purchase Simeprevir | Simeprevir cost | Simeprevir manufacturer | order Simeprevir | Simeprevir distributor | buy 923604-59-5 | 923604-59-5 Supplier | purchase 923604-59-5 | 923604-59-5 cost | 923604-59-5 manufacturer | order 923604-59-5 | 923604-59-5 distributor