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ST7612AA1

Name: ST7612AA1
Brand: Adooq Bioscience
SKU: A14418
Availability: InStock

Cat. No. A14418 CAS 1428535-92-5

HDAC inhibitor

ST7612AA1 is a new and potent HDAC inhibitor with potential anticancer activity.

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Biological Activity

Cellular Effect

Cell Line	Activity	Value	Description	Reference
HCT-116	IC50	0.075 μM	Cytotoxicity against human HCT116 cells after 24 hrs by SRB assay	[PMID: 25233084]
NCI-H460	IC50	0.005 μM	Inhibition of HDAC-mediated histone H4 deacetylation in human NCI-H460 cells after 3 hrs by Western blot analysis	[PMID: 25233084]
NCI-H460	IC50	0.07 μM	Cytotoxicity against human NCI-H460 cells after 24 hrs by SRB assay	[PMID: 25233084]
NCI-H460	IC50	0.2 μM	Inhibition of HDAC-mediated tubulin deacetylation in human NCI-H460 cells after 3 hrs by Western blot analysis	[PMID: 25233084]

Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	1428535-92-5
Applications	HDAC inhibitor
Formula	C₂₀H₂₇N₃O₄S
Molecular Weight	405.51
SMILES	CC(SCCCCC[C@H](NC([C@@H](CC1)NC1=O)=O)C(NC2=CC=CC=C2)=O)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.