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TH287

MTH1 inhibitor

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Catalog No. A15536

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
TH287 10mg A15536-10

Regular Price: $90.00

Special Price: $72.00

TH287 25mg A15536-25

Regular Price: $250.00

Special Price: $200.00

TH287 50mg A15536-50

Regular Price: $480.00

Special Price: $384.00

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

TH287 is a potent inhibitor of MTH1 (NUDT1) with an IC50 value of 0.8 nM, less potent for MTH2, NUDT5, NUDT12, NUDT14, and NUDT16,

TH287

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Chemical Information

Catalog Num A15536
Actions Inhibitor
M. Wt 269.13
Formula C11H10Cl2N4
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1609960-30-6
Synonyms TH-287, TH 287
SMILES code CNC1=NC(=NC(=C1)C2=C(C(=CC=C2)Cl)Cl)N
Chemical Name 6-(2,3-dichlorophenyl)-N4-methylpyrimidine-2,4-diamine

Biological Activity

Description
TH287 is a potent inhibitor of MTH1 (NUDT1) with an IC50 value of 0.8 nM, less potent for MTH2, NUDT5, NUDT12, NUDT14, and NUDT16,
Targets
MTH1 (NUDT1)
0.8 nM

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