Triciribine phosphate (NSC-280594)

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AKT Inhibitor

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Catalog No. A11033

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
Triciribine phosphate 5mg A11033-5

Regular Price: $80.00

Special Price: $64.00

Triciribine phosphate 10mg A11033-10

Regular Price: $130.00

Special Price: $104.00

Triciribine phosphate 50mg A11033-50

Regular Price: $380.00

Special Price: $304.00

Triciribine phosphate 100mg A11033-100

Regular Price: $680.00

Special Price: $544.00

Triciribine phosphate 10mM * 1mL in DMSO A11033-10mM-D

Regular Price: $85.00

Special Price: $68.00

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

Triciribine phosphate inhibits the phosphorylation, activation, and signalling of Akt-1, -2, and -3, which may result in the inhibition of Akt-expressing tumor cell proliferation.

Triciribine phosphate (NSC-280594)

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Chemical Information

Catalog Num A11033
Actions Inhibitor
M. Wt 400.3
Formula C13H17N6O7P
Solubility DMSO
Purity >98%
Storage at -20°C 2 years
CAS No. 61966-08-3
Synonyms VQD-002,TCN-P
SMILES code CN1C2=NC=NC3=C2C(=CN3[[email protected]]4[C@@H]([C@@H]([[email protected]](O4)COP(=O)(O)O)O)O)C(=N1)N
Chemical Name ((2R,3S,4R,5R)-5-(3-amino-5-methyl-1,4,5,6,8-pentaazaacenaphthylen-1(5H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl dihydrogen phosphate

Biological Activity

Description
Triciribine phosphate inhibits the phosphorylation, activation, and signalling of Akt-1, -2, and -3, which may result in the inhibition of Akt-expressing tumor cell proliferation.

Solubility

Solubility (25°C) * In vitro DMSO 64 mg/mL (199.81 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
In vivo 1% DMSO/30% polyethylene glycol/1% Tween 80 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

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