YK 4-279
YK 4-279 is an inhibitor of RNA Helicase A (RHA) binding to the oncogenic transciption factor EWS-FLI1.
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Adooq Products cited in reputable paper
Adooq's YK 4-279 has been cited by 1 publications
- Christopher M Schafer, .et al. , Proc Natl Acad Sci U S A, 2020, Oct 20;117(42):26494-26502 PMID: 33020273
Biological Activity
| Description | YK 4-279 is an inhibitor of RNA Helicase A (RHA) binding to the oncogenic transciption factor EWS-FLI1. | |||||
|---|---|---|---|---|---|---|
| Targets |
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| Cell Research |
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Product Information
| Catalog Num | A11612 |
|---|---|
| Formula | C17H13Cl2NO4 |
| Molecular Weight | 366.2 |
| CAS Number | 1037184-44-3 |
| SMILES | COC1=CC=C(C=C1)C(=O)CC2(C3=C(C=CC(=C3NC2=O)Cl)Cl)O |
| Synonyms | YK-4-279 |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
Solubility
| In vitro | DMSO | 66 mg/mL (180.23 mM) | |
| Water | Insoluble | ||
| Ethanol | Warmed: 46 mg/mL (125.61 mM) | ||
| * <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. | |||
Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 27.31 mL | 136.54 mL | 273.07 mL |
| 0.5 mM | 5.46 mL | 27.31 mL | 54.61 mL |
| 1 mM | 2.73 mL | 13.65 mL | 27.31 mL |
| 5 mM | 0.55 mL | 2.73 mL | 5.46 mL |
Useful Calculator
This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:
Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)
Please check COA/MSDS for correct molecular weight.
Calculate the dilution required to prepare a stock solution.This equation is commonly abbreviated as: C1V1 = C2V2
