Fig. 1 · Structure

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1-(1-Naphthyl)piperazine hydrochloride

5-HT Receptor Modulator

1-(1-Naphthyl)piperazine hydrochloride is a potent modulator of the 5-HT receptor system, functioning as an agonist at the 5-HT1A receptor while antagonizing the 5-HT2A receptor. This compound has demonstrated significant biological activity by inducing apoptosis in various cell types. Additionally, it exhibits potential in combatting immunosuppression and preventing photocarcinogenesis, making it a valuable tool for research in neuroscience and cancer studies.

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Specifications

Manufacturer Adooq Bioscience
Actions Modulator
CAS Number 104113-71-5
Applications 5-HT Receptor Modulator
Formula C14H17ClN2
Molecular Weight 248.75
Synonyms 1-NP hydrochloride; 1-Naphthylpiperazine hydrochloride
SMILES
C12=C(C=CC=C2N3CCNCC3)C=CC=C1.Cl

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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