Fig. 1 · Structure
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1,12-Dibromododecane
PROTAC Linker
1,12-Dibromododecane is a versatile PROTAC linker that plays a crucial role in the synthesis of Proteolysis Targeting Chimeras (PROTACs). This compound exhibits effective coupling capabilities, facilitating the selective degradation of target proteins via the ubiquitin-proteasome system. Its unique structure allows for the precise design of bifunctional molecules, making it valuable for research in targeted protein degradation and related therapeutic applications.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 3344-70-5 |
| Applications | PROTAC Linker |
| Formula | C12H24Br2 |
| Molecular Weight | 328.13 |
| SMILES | BrCCCCCCCCCCCCBr |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.