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1,2-Diarachidonoyl-sn-glycero-3-phosphoethanolamine

Phospholipid Phosphatidylethanolamine

1,2-Diarachidonoyl-sn-glycero-3-phosphoethanolamine (DAPE) is a phospholipid derivative of phosphatidylethanolamine. DAPE does not significantly affect protein phosphatase PP2A activity or inhibit insulin-stimulated GLUT4 translocation, distinguishing it from other phosphatidylethanolamines. This unique profile makes DAPE a valuable tool for research in lipid signaling and metabolic functions, facilitating the study of cellular processes related to insulin sensitivity and lipid metabolism.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	5634-86-6
Applications	Phospholipid Phosphatidylethanolamine
Formula	C₄₅H₇₄NO₈P
Molecular Weight	788.04
Synonyms	DAPE
SMILES	CCCCC/C=C\C/C=C\C/C=C\C/C=C\CCCC(O[C@@H](COP(OCCN)(O)=O)COC(CCC/C=C\C/C=C\C/C=C\C/C=C\CCCCC)=O)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.