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1,2-Didehydrotanshinone IIA

AChE/BChE Inhibitor

1,2-Didehydrotanshinone IIA is an inhibitor of acetylcholinesterase (AChE) and butyrylcholinesterase (BChE), demonstrating an IC50 value of 5.98 μM for BChE. Additionally, this compound acts as an indoleamine 2,3-dioxygenase (IDO) inhibitor, with an IC50 value of 4.68 µM. Its dual inhibitory activity positions 1,2-Didehydrotanshinone IIA as a valuable reagent for research into neurodegenerative diseases and immune modulation.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	119963-50-7
Applications	AChE/BChE Inhibitor
Formula	C₁₉H₁₆O₃
Molecular Weight	292.33
SMILES	O=C1C(C2=C(C3=C1C(C=CCC4(C)C)=C4C=C3)OC=C2C)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.