• Sign In
  • FAQ
  • Create an Account
Currency
USD currency flagUSD
Toggle Nav
My Cart
Menu
Account
Settings
Currency
USD currency flagUSD

1,2-Didehydrotanshinone IIA

Catalog No.: A75771
AChE/BChE Inhibitor
1,2-Didehydrotanshinone IIA is an inhibitor of acetylcholinesterase (AChE) and butyrylcholinesterase (BChE), demonstrating an IC50 value of 5.98 μM for BChE. Additionally, this compound acts as an indoleamine 2,3-dioxygenase (IDO) inhibitor, with an IC50 value of 4.68 µM. Its dual inhibitory activity positions 1,2-Didehydrotanshinone IIA as a valuable reagent for research into neurodegenerative diseases and immune modulation.
1,2-Didehydrotanshinone IIA 119963-50-7 AChE/BChE Inhibitor
Grouped product items
Size Stock
5mg
10mg
50mg
Bulk Size
Bulk Discount
Bulk Inquiry
Notify me when the price drops
Notify me when this product is in stock
Free Delivery on orders over $500
Research use only. We do not sell to patients.
Data Sheet SDS

Loading distributor info...

Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
Description1,2-Didehydrotanshinone IIA is an inhibitor of acetylcholinesterase (AChE) and butyrylcholinesterase (BChE), demonstrating an IC50 value of 5.98 μM for BChE. Additionally, this compound acts as an indoleamine 2,3-dioxygenase (IDO) inhibitor, with an IC50 value of 4.68 µM. Its dual inhibitory activity positions 1,2-Didehydrotanshinone IIA as a valuable reagent for research into neurodegenerative diseases and immune modulation.
Product Information
Catalog NumA75771
FormulaC19H16O3
Molecular Weight292.33
CAS Number119963-50-7
SMILESO=C1C(C2=C(C3=C1C(C=CCC4(C)C)=C4C=C3)OC=C2C)=O
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

  • Mass

    Concentration

    Volume

    Molecular Weight

Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

  • C1

    V1

    C2

    V2

Neuronal Signaling > AChE